Tag: Cerebral Folate Deficiency - Metabolic Learning Resource

Transgenerational Effects and Heritability of Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorder

Frye, R.E.; Cohen, I.L.; Sequeira, J.M.; Hill, Z.; Espinoza, A.; Brown, W.T.; Mevs, C.; Marchi, E.; Flory, M.; Jenkins, E.C.; et al. Transgenerational Effects and Heritability of Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorder. Int. J. Mol. Sci. 2025, 26, 8293.

Autism, Cerebral Folate Deficiency, Folate, FRA Antibodies

Read Article

Scientific Articles

Folate Receptor Alpha Autoantibodies in the Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Population

Wells, L.; O’Hara, N.; Frye, R.E.; Hullavard, N.; Smith, E. J. Pers. Med. 2024, 14, 166.

Biomarkers, Cerebral Folate Deficiency, Folate, IVIG, Metabolism, PANDAS, PANS

Read Article

Scientific Articles

Binding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder

Frye RE, McCarty PJ, Werner BA, Scheck AC, Collins HL, Adelman SJ, Rossignol DA, Quadros EV. J Pers Med. 1 Jan 2024.

Autism, Biomarkers, Cerebral Folate Deficiency, Folinic Acid, New, Treatment

Read Article

Scientific Articles

The Soluble Folate Receptor in Autism Spectrum Disorder: Relation to Autism Severity and Leucovorin Treatment.

Frye RE, Lane A, Worner A, Werner BA, McCarty PJ, Scheck AC, Collins HL, Adelman SJ, Quadros EV, Rossignol DA. The Soluble Folate Receptor in Autism Spectrum Disorder: Relation to Autism Severity and Leucovorin Treatment. J Pers Med. 2022 Dec 8;12(12):2033. doi: 10.3390/jpm12122033. PMID: 36556254; PMCID: PMC9786140.

Autism, Biomarkers, Cerebral Folate Deficiency, Metabolism, Mitochondrial Dysfunction, Published Articles

Read Article

Scientific Articles

Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis

Rossignol DA, Frye RE. Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis. J Pers Med. 2021 Nov 3;11(11):1141. doi: 10.3390/jpm11111141. Erratum in: J Pers Med. 2022 Apr 29;12(5): PMID: 34834493; PMCID: PMC8622150.

Autism, Cerebral Folate Deficiency, Folate, Leucovorin, Meta-Analysis, Published Articles, Treatment

Read Article

Scientific Articles

Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder

Autism, Cerebral Folate Deficiency, Folate, Leucovorin, Published Articles, Treatment

Read Article

Scientific Articles

Folate metabolism abnormalities in autism: potential biomarkers

Frye RE, Slattery JC, Quadros EV. Folate metabolism abnormalities in autism: potential biomarkers. Biomark Med. 2017 Aug;11(8):687-699. doi: 10.2217/bmm-2017-0109. Epub 2017 Aug 3. PMID: 28770615.

Autism, Biomarkers, Cerebral Folate Deficiency, Folate, Published Articles

Read Article

Scientific Articles

Cerebral folate receptor autoantibodies in autism spectrum disorder

Frye RE, Sequeira JM, Quadros EV, James SJ, Rossignol DA. Cerebral folate receptor autoantibodies in autism spectrum disorder. Mol Psychiatry. 2013 Mar;18(3):369-81. doi: 10.1038/mp.2011.175. Epub 2012 Jan 10. PMID: 22230883; PMCID: PMC3578948.

Autism, Cerebral Folate Deficiency, Folate, FRA Antibodies, Leucovorin, Published Articles, Treatment

Read Article

Parent Articles